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Entity 1
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Relationship
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Entity 2
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Article
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| mitotane | associated-with | etoposide | Mitotane associated with etoposide, doxorubicin, and cisplatin in the treatment of advanced adrenocortical carcinoma. Italian Group for the Study of Adrenal Cancer. | 1 | 34.4474 |
| irinotecan | follow | etoposide | Phase I/II study of weekly irinotecan and paclitaxel in patients with SCLC. | 1 | 34.3662 |
| etoposide | induced | apoptosis | Dexamethasone and etoposide induce apoptosis in rat thymocytes from different phases of the cell cycle. | 17 | 31.8254 |
| leukaemia | following | etoposide | [The value of etoposide (VP-16) in the therapy of refractory ovarian cancer] | 1 | 31.6739 |
| breast cancer | including | etoposide | Autologous tandem transplantation: almost complete reduction of neutropenic fever following the second transplantation by ex vivo expanded autologous myeloid postprogenitor cells. | 1 | 31.2832 |
| tumors | associated-with | etoposide | The management of gestational trophoblastic tumors with etoposide, methotrexate, and actinomycin D. | 1 | 30.7012 |
| clostridial infection | associated-with | etoposide | Clostridial myonecrosis in association with etoposide therapy presenting as severe thigh pain. | 1 | 30.7012 |
| apoptosis | following | etoposide | Herbimycin A accelerates the induction of apoptosis following etoposide treatment or gamma-irradiation of bcr/abl-positive leukaemia cells. | 2 | 30.5174 |
| doxorubicin | drugs | etoposide | Chemosensitivity testing of fresh human gastric cancer with highly purified tumour cells using the MTT assay. | 1 | 30.4431 |
| P-gp | resistant | etoposide | A new quinoline derivative MS-209 reverses multidrug resistance and inhibits multiorgan metastases by P-glycoprotein-expressing human small cell lung cancer cells. | 1 | 30.2121 |
| etoposide | caused | P815 tumor | Treatment of the P815 murine mastocytoma with cisplatin or etoposide up-regulates cell-surface Fas (CD95) expression and increases sensitivity to anti-Fas antibody-mediated cytotoxicity and to lysis by anti-CD3-activated killer-T cells. | 1 | 29.7013 |
| acute nonlymphocytic leukemia | following | etoposide | Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung. | 1 | 29.5174 |
| etoposide | studied-in | cancer | Pharmacokinetics of etoposide in cancer patients treated with high-dose etoposide and with dexrazoxane (ICRF-187) as a rescue agent. | 1 | 28.6074 |
| etoposide | replace | lomustine | Lomustine and melphalan cannot be replaced by cyclophosphamide and etoposide without reducing efficacy in MOPPEBVCAD chemotherapy for advanced Hodgkin's disease. | 1 | 28.1593 |
| etoposide | derived-from | etoposide phosphate | Bioequivalence investigation of high-dose etoposide and etoposide phosphate in lymphoma patients. | 1 | 27.8947 |
| etoposide | effective | leukocytosis | [Pleural involvement in the course of chronic myelomonocytic leukemia and the development of multiple colonic perforation due to leukemic infiltration in the acute leukemia phase] | 1 | 27.6542 |
| etoposide phosphate | bioequivalent | etoposide | Bioequivalence assessment of etoposide phosphate and etoposide using pharmacodynamic and traditional pharmacokinetic parameters. | 1 | 27.637 |
| etoposide | analogous | mitoxantrone | Differences in the longevity of topo IIalpha and topo IIbeta drug-stabilized cleavable complexes and the relationship to drug sensitivity. | 1 | 27.3226 |
| etoposide | sensitive | topotecan | Activity of topotecan, a new topoisomerase I inhibitor, against human tumor colony-forming units in vitro. | 1 | 27.2265 |
| serum cholesterol | lower | etoposide | Influence of etoposide on the retention of radiolabeled low-density lipoprotein in the arterial wall. | 1 | 27.1612 |
| etoposide | superior | vincristine | Ifosfamide and etoposide are superior to vincristine and melphalan for pediatric metastatic rhabdomyosarcoma when administered with irradiation and combination chemotherapy: a report from the Intergroup Rhabdomyosarcoma Study Group. | 1 | 26.8777 |
| etoposide | active | ovarian carcinoma | Combination therapy with carboplatin/cisplatin/ifosfamide/etoposide in ovarian cancer. | 1 | 26.8493 |
| etoposide | inhibitors | enzyme | Effects of antileukemic agents on the activity of terminal deoxynucleotidyl transferase from human normal thymic and leukemic cells "in vitro". | 1 | 26.1358 |
| etoposide | treatment | human bladder cancer | Therapeutic effect of CDDP and VP-16 against human bladder cancers. | 1 | 25.5326 |
| etoposide | killed | pancreatic cancer | [Effect of etoposide on a human pancreatic cancer cell line exposed to high dose X-ray irradiation] | 1 | 25.4188 |
| gossypol | efficient | etoposide | (-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance. | 1 | 24.9512 |
| quinolone | equipotent | etoposide | Cytotoxicity of quinolones toward eukaryotic cells. Identification of topoisomerase II as the primary cellular target for the quinolone CP-115,953 in yeast. | 1 | 24.2958 |
| etoposide | synergistic | L1210 leukemia | Cytotoxic synergism between trimetrexate and etoposide. Evidence that trimetrexate potentiates etoposide-induced protein-associated DNA strand breaks in L1210 leukemia cells through alterations in intracellular ATP concentrations. | 1 | 23.6391 |
| etoposide | drugs | topoisomerase | Sister-chromatid exchanges, chromosomal aberrations and cytotoxicity produced by topoisomerase II-targeted drugs in sensitive (A2780) and resistant (A2780-DX3) human ovarian cancer cells: correlations with the formation of DNA double-strand breaks. | 1 | 22.7918 |
| cell lung cancer | treated-with | etoposide | High-dose etoposide therapy for extensive small cell lung cancer: a Cancer and Leukemia Group B Study. | 3 | 19.0078 |
| carboplatin | combined-with | etoposide | Autologous bone marrow transplantation in solid tumors. | 3 | 18.6722 |
| cyclophosphamide | administered-to | etoposide | [Combination of etoposide with cisplatin or cyclophosphamide in the treatment of mouse Lewis lung carcinoma] | 1 | 16.6554 |
| lymphoma | treated-with | etoposide | Multiple cycles of high dose chemotherapy supported by hematopoietic progenitor cells as treatment for patients with advanced malignancies. | 1 | 15.8414 |
| gemcitabine | compared-with | etoposide | The use of gemcitabine in non-small-cell lung cancer. Provincial Lung Cancer Disease Site Group. Provincial Systemic Treatment Disease Site Group. | 1 | 14.0208 |
| teniposide | substituted-for | etoposide | Acute hypersensitivity reactions to etoposide in a VEPA regimen for Hodgkin's disease. | 1 | 13.9921 |
| sarcoma | treated-with | etoposide | Treatment of epidemic Kaposi's sarcoma with etoposide or a combination of doxorubicin, bleomycin, and vinblastine. | 2 | 13.9713 |
| leucovorin | combined-with | etoposide | The UFT/leucovorin/etoposide regimen for the treatment of advanced gastric cancer. Oncopaz Cooperative Group. | 1 | 13.9699 |
| ovarian cancer | treated-with | etoposide | Etoposide (VP-16-213) plus cis-diamminedichloroplatinum as salvage therapy in advanced epithelial ovarian cancer. | 1 | 13.9534 |
| vincristine | alternating-with | etoposide | Superiority of alternating non-cross-resistant chemotherapy in extensive small cell lung cancer. A multicenter, randomized clinical trial by the National Cancer Institute of Canada. | 2 | 13.7975 |
| mice | treated-with | etoposide | Combined oral administration of etoposide and arabinofuranosylcytosine-5'-stearylphosphate enhances the antitumor effect against P388 ascites tumors. | 4 | 13.6051 |
| cell lung carcinoma | treated-with | etoposide | Treatment of small cell lung cancer: a single institutional experience. | 1 | 13.477 |
| neuroblastoma | treated-with | etoposide | Oral etoposide for refractory and relapsed neuroblastoma. | 1 | 13.2089 |
| bleomycin | alternating-with | etoposide | Cytoreductive surgery in disseminated non-seminomatous germ cell tumours of testis. | 1 | 12.5482 |
| Amifostine | decreased | etoposide | Amifostine does not protect malignant lymphoma cell lines from the cytotoxic effects of various chemotherapeutics in vitro. | 1 | 12.1265 |
| tubulin | induced-with | etoposide | Estimation of changes in tubulin induced with etoposide in human leukemia cells line K-562 by immunofluorescence microscope. | 1 | 11.7167 |
| gastric cancer | treated-with | etoposide | Phase II trial of etoposide, doxorubicin (Adriamycin), and cisplatin (EAP regimen) in advanced gastric cancer. | 2 | 11.6051 |
| tamoxifen | enhanced | etoposide | Tamoxifen modulation of etoposide cytotoxicity involves inhibition of protein kinase C activity and insulin-like growth factor II expression in brain tumor cells. | 1 | 11.2145 |
| hamsters | treated-with | etoposide | Meiotic stage-dependent induction of chromosome aberrations in Chinese hamster primary oocytes exposed to topoisomerase II inhibitor etoposide. | 1 | 10.6051 |
| acute lymphoblastic leukemia | treated-with | etoposide | Secondary acute myeloid leukemia in children with acute lymphoblastic leukemia treated with etoposide. | 1 | 10.6051 |
| olfactory neuroblastoma | treated-with | etoposide | Neoadjuvant etoposide, ifosfamide, and cisplatin for the treatment of olfactory neuroblastoma. | 1 | 10.6051 |
