Relations for proline

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Entity 1	Relationship	Entity 2	Article	Frequency	Score
alanine	replaced	proline	Characterization of proline-containing alpha-helix (helix F model of bacteriorhodopsin) by molecular dynamics studies.	3	36.9139
serine	replaced	proline	A missense mutation in the FALDH gene identified in Sjögren-Larsson syndrome patients originating from the northern part of Sweden.	3	36.1178
glutamate	produces	proline	II. Glutamine and glutamate.	1	34.0208
lysine	effective	proline	Delineation of sodium-stimulated amino acid transport pathways in rabbit kidney brush border vesicles.	1	32.6889
proline	containing	peptide	Proline specific endo- and exopeptidases.	3	31.0746
Cysteine	replaced	proline	The crystal structure of TrxA(CACA): Insights into the formation of a [2Fe-2S] iron-sulfur cluster in an Escherichia coli thioredoxin mutant.	1	30.9938
acylphosphatase	associated-with	proline	Initial denaturing conditions influence the slow folding phase of acylphosphatase associated with proline isomerization.	1	30.7012
proline	associated-with	breast cancer	An allelic variant at the ATM locus is implicated in breast cancer susceptibility.	1	30.7012
proline	cause	anemia	Fascioliasis: similarities of the anemia in rats to that produced by infused proline.	1	29.7013
proline	following	proteolysis	Reutilization of precursor following axonal transport of [3H]proline-labeled protein.	1	29.5174
proline	follow	lysine	Influence of the postoperative state on the intracellular free amino acids in human muscle tissue.	1	29.5174
proline	follow	N-terminal arginine	An aminopeptidase activity in bovine pituitary secretory vesicles that cleaves the N-terminal arginine from beta-lipotropin60-65.	1	29.5174
L-amino acids	including	proline	Diastereoselectivities realized in the amino acid catalyzed aldol cyclizations of triketo acetonides of differing ring size.	1	29.4205
liver cirrhosis	had	proline	Serum free proline and free hydroxyproline in patients with chronic liver disease.	1	29.4103
proline	replaced	leucine	Cloning and functional expression of poly(ADP-ribose) polymerase cDNA from Sarcophaga peregrina.	2	29.1593
proline	replaced-with	alanine	Different structural requirements at specific proline residue positions in the conserved proline-rich region of cytochrome P450 2C2.	2	29.1593
hormone	contains	proline	Pre-proparathyroid hormone: fidelity of the translation of parathyroid messenger RNA by extracts of wheat germ.	1	29.0746
novel proteins	contain	proline	Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: role in epithelial cancer cell invasion, proliferation and nuclear regulation.	1	29.0746
membrane transport proteins	contain	proline	Characterization of proline-containing alpha-helix (helix F model of bacteriorhodopsin) by molecular dynamics studies.	1	29.0746
albumin microspheres	containing	proline	Synthesis and characterization of magnetically responsive albumin microspheres containing cis-hydroxyproline for scar inhibition.	1	29.0746
proline	contained-in	procollagen	Termination of procollagen chain synthesis by puromycin. Evidence that assembly and secretion require a COOH-terminal extension.	1	29.0746
proline	related-to	pyruvate	Proline metabolism in sepsis, cirrhosis and general surgery. The peripheral energy deficit.	1	29.0586
redox enzyme	involved-in	proline	The Escherichia coli biotin regulatory system: a transcriptional switch.	1	29.052
proline	produced-from	L-citrulline	Arginine catabolism by Treponema denticola.	1	28.9769
proline	occurs-with	isoproterenol	Purification of proline-rich proteins from parotid glands of isoproterenol-treated rats.	1	28.7744
sarcosine	replace	proline	Substrate specificity of CDC2 kinase from human HeLa cells as determined with synthetic peptides and molecular modeling.	1	28.1593
tryptophan	replacing	proline	Human immunodeficiency virus type 1 Brazilian subtype B variant showed an increasing avidity of the anti-V3 antibodies over time compared to the subtype B US/European strain in São Paulo, Brazil.	1	28.1593
6-glucosidase	replaced-with	proline	Multiple proline substitutions cumulatively thermostabilize Bacillus cereus ATCC7064 oligo-1,6-glucosidase. Irrefragable proof supporting the proline rule.	1	28.1593
proline	replaced	glutamine	A new unstable haemoglobin variant: Hb Shanghai [beta 131(H9)Gln----Pro] found in China.	1	28.1593
proline	replace	ammonia	AUA1, a gene involved in ammonia regulation of amino acid transport in Saccharomyces cerevisiae.	1	28.1593
proline	replaced-with	Cysteine	Directed mutagenesis of dihydrofolate reductase.	1	28.1593
proline	replaced	Casamino acids	Effect of growth rate on plasmid maintenance by Escherichia coli HB101(pAT153).	1	28.1593
proline	replaced	glycine	Structure of the extra-membranous domain of the beta-subunit of (Na,K)-ATPase revealed by the sequences of its tryptic peptides.	1	28.1593
proline	identified-at	C-termini	Carboxyl-terminal residues of mammalian fibrinogen and fibrin.	1	28.0148
proline	derived	dipeptidyl peptidase	Potent and selective proline derived dipeptidyl peptidase IV inhibitors.	1	27.8947
kinase	involved-in	proline	Studies on selection and characterization of a stress-tolerant sugarcane cell line.	1	27.631
45-kDa protein	higher	proline	Electrophoretic method for the identification of a haze-active protein in grape seeds.	1	27.5221
diabetes	due	proline	Islet amyloid in type 2 (non-insulin-dependent) diabetes.	1	27.5132
L-lactate	present	proline	Detection of L-lactate in polyethylene glycol solutions confirms the identity of the active-site ligand in a proline dehydrogenase structure.	1	27.4831
alpha-hydroxy acid	incorporated-at	proline	Probing the role of a conserved M1 proline residue in 5-hydroxytryptamine(3) receptor gating.	1	27.3386
proline	incorporated-into	polypeptide	Identification and partial characterization of three low-molecular-weight collagenous polypeptides synthesized by chondrocytes cultured within collagen gels in the absence and in the presence of fibronectin.	1	27.3386
proline	incorporated-into	wound collagen	Collagen deposition and mechanical strength of colon anastomoses and skin incisional wounds of rats.	1	27.3386
proteins	containing	proline	Experimental studies of folding kinetics and structural dynamics of small proteins.	4	26.9861
proline	greater	piglets	Arginine synthesis does not occur during first-pass hepatic metabolism in the neonatal piglet.	1	26.8522
proline	important	substrate	Role of the pyrrolidine ring of proline in determining the substrate specificity of cdc2 kinase or cdk5.	1	26.4293
proline	competes-with	L-azetidine-2-carboxylic acid	Role of ascorbic acid in the regulation of proliferation in osteoblast-like MC3T3-E1 cells.	1	26.1648
tumor	retained	proline	The influence of the p53 codon 72 polymorphism on ovarian carcinogenesis and prognosis.	1	25.9904
ribonuclease	characteristic	proline	Tests of the simple model of Lin and Brandts for the folding kinetics of ribonuclease A.	1	25.9558
proline	lack	hydrogen	Probing the role of a conserved M1 proline residue in 5-hydroxytryptamine(3) receptor gating.	1	25.9488
protein	rich	proline	Expression of post-transcriptional regulatory gene of HTLV-I, rex, in Escherichia coli.	10	25.832

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