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| enzyme | active | pyruvate | Purification, characterization and identification of rat liver histidine-pyruvate aminotransferase isoenzymes. |
| Voriconazole | active | itraconazole | In vitro studies of activity of voriconazole (UK-109,496), a new triazole antifungal agent, against emerging and less-common mold pathogens. |
| methanesulfonate | active | P388 leukemia | 2-Chloroethyl (methylsulfonyl)methanesulfonate and related (methylsulfonyl)methanesulfonates. Antineoplastic activity in vivo. |
| enzyme | active | chondroitin | Purification and partial characterization of hyaluronate lyase (EC 4.2.2.1) from Propionibacterium acnes. |
| ceftriaxone | active | ceftazidime | Comparative susceptibilities of Klebsiella species, Enterobacter species, and Pseudomonas aeruginosa to 11 antimicrobial agents in a tertiary-care university hospital. |
| ceftazidime | active | moxalactam | Comparison of the pharmacokinetics of ceftazidime and moxalactam and their microbiological correlates in volunteers. |
| enzyme | active | oestrone | Partial purification of a human liver sulphotransferase active towards bile salts. |
| ciprofloxacin | active | enoxacin | Multiple drug-resistant Corynebacteriaceae: in vitro and in vivo (murine) studies. |
| cefoperazone | active | moxalactam | In vitro evaluation of cefoperazone. |
| enzyme | active | phosphatidylcholine hydroperoxide | Oxidative stress response in yeast: purification and some properties of a membrane-bound glutathione peroxidase from Hansenula mrakii. |
| enzyme | active | Nocardia | [Carbohydrate metabolic characteristics of coryneform bacteria] |
| trimethoprim | active | Borrelia | In vitro activity of trimethoprim against Borrelia burgdorferi. |
| amitriptyline | active | mouse | Pharmacological studies on YM992, a novel antidepressant with selective serotonin re-uptake inhibitory and 5-HT2A receptor antagonistic activity. |
| protease | active | 100 mM phosphate | Processing of an NH2-terminally extended thermostable alpha-amylase by Bacillus subtilis alkaline protease. |
| enzyme | active | paracetamol | Purification and immunochemical characterization of a rat liver sulphotransferase conjugating paracetamol. |
| linezolid | active | methicillin | Ciprofloxacin- and methicillin-resistant staphylococcus aureus susceptible to moxifloxacin, levofloxacin, teicoplanin, vancomycin and linezolid. |
| enzyme | active | 1-butanol | Mitochondrial alcohol dehydrogenase from ethanol-grown Euglena gracilis. |
| enzyme | active | 25-hydroxycholesterol | Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone. |
| enzyme | active | phosphotyrosyl proteins | Identification of a protein-tyrosine phosphatase from human platelet membranes by an immobilon-based solid phase assay. |
| enzyme | active | energy deficiency | Pyruvate carboxylation in neurons. |
| enzyme | active | myristoyl | Purification and characterization of a lysophospholipase from human amnionic membranes. |
| pemetrexed | active | gastric cancer | Cytotoxic effects of pemetrexed in gastric cancer cells. |
| enzyme | active | propionyl | Kinetics and catalytic properties of coenzyme A transferase from Peptostreptococcus elsdenii. |
| enzyme | active | isomaltose | Purification and properties of an oligo-1,6-D-glucosidase from an alkalophilic Bacillus species. |
| enzyme | active | 6-aminohexanoic acid | Purification and characterization of 6-aminohexanoic-acid-oligomer hydrolase of Flavobacterium sp. Ki72. |
| enzyme | active | 3-hydroxykynurenine | Intracellular localization and characterization of 3-hydroxykynureninase in human liver. |
| protein | active | menadione | The 30 kDa protein co-purified with chick liver glutathione S-transferases is a carbonyl reductase. |
| enzyme | active | pregnenolone | Hydroxysteroid sulfotransferase activity in the rat brain and liver as a function of age and sex. |
| enzyme | active | thrombosis | Potential cardiovascular effects of COX-2 selective nonsteroidal antiinflammatory drugs. |
| apomorphine | active | dog | A role for dopamine in growth hormone regulation in the dog. |
| clarithromycin | active | azithromycin | Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated f |
| clarithromycin | active | Borrelia | History of macrolide use in pediatrics. |
| sulfone | active | sulfoxide | Antiinflammatory activity of methionine, methionine sulfoxide and methionine sulfone. |
| lidocaine | active | KCl | Pharmacological evaluation of the angiotensin, kinin, and neurokinin receptors on the rabbit vena cava. |
| tyramine | active | yeast | The relationship of chromium to the glucose tolerance factor. II. |
| etoposide | active | ovarian carcinoma | Combination therapy with carboplatin/cisplatin/ifosfamide/etoposide in ovarian cancer. |
| ethylamine | active | histamine | Effect of histamine on cyclic AMP levels in the submandibular gland. |
| cefepime | active | moxalactam | Therapeutic studies of cefepime (BMY 28142) in murine meningitis and pharmacokinetics in neonatal rats. |
| cefamandole | active | cefuroxime | Relationship between cefamandole and cefuroxime activity against oxacillin-resistant Staphylococcus epidermidis and oxacillin resistance phenotype. |
| enzyme | active | B6 mice | Differential effects of fat and sucrose on body composition in A/J and C57BL/6 mice. |
| enzyme | active | tumorigenesis | Irinotecan, cisplatin/carboplatin, and COX-2 inhibition in small-cell lung cancer. |
| enzyme | active | valproic | Characterization of a renal medium chain acyl-CoA synthetase responsible for glycine conjugation in mouse kidney mitochondria. |
| enzyme | active | malondialdehyde | Bovine lens aldehyde dehydrogenase. Kinetics and mechanism. |
| enzyme | active | protein tyrosine kinase | Expression, purification and characterization of focal adhesion kinase using a baculovirus system. |
| enzyme | active | carboxylase | Vitamin K dependent in vitro production of prothrombin. |
| tinidazole | active | G. lamblia | In vitro susceptibility of Giardia lamblia trophozoites to metronidazole and tinidazole. |
| cefpodoxime | active | penicillin | In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae. |
| cefpodoxime | active | cefixime | [Comparative antibacterial activity of cefpodoxime against Haemophilus influenzae, Streptococcus pyogenes, Streptococcus pneumoniae and Moraxella catarrhalis] |
| imidazole acetic acid | active | muscimol | The GABA agonist THIP a muscimol analogue, does not interfere with the benzodiazepine binding site on rats cortical membranes. |
| 5'-nucleotidase | active | rat | Species-related difference in the heart sarcolemmal enzyme activities. |
