Relationships for binds-to
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| substrate | binds-to | enzyme | Evidence against a covalent intermediate in the adenosine triphosphate phosphoribosyltransferase reaction of histidine biosynthesis. |
| enzyme | binds-to | substrate | Analysis of the kinetics of phospholipid activation of cobra venom phospholipase A2. |
| protein | binds-to | carbohydrate | [Studies on the level and composition of protein bound carbohydrate components in the serum and blood vessel wall of normal and arteriosclerotic subjects.] |
| methotrexate | binds-to | dihydrofolate | Methotrexate polyglutamate synthesis by cultured human breast cancer cells. |
| protein | binds-to | oligonucleotide | A triplex DNA-binding protein from human cells: purification and characterization. |
| protein | binds-to | fibrinogen | M3-protein with close sequence homology to M12 protein binds fibrinogen, albumin, fibronectin, but not to any subclass of IgG-localization of binding regions. |
| protein | binds-to | glutamate | Interactions of a glutamate-aspartate binding protein with the glutamate transport system of Escherichia coli. |
| heparin | binds-to | collagen | Some characteristics of collagen-heparin complex. |
| nucleotide | binds-to | enzyme | Interaction of 1,N6-ethenoadenine derivatives of triphosphopyridine and reduced triphosphopyridine nucleotides with dihydrofolate reductase from amethopterin-resistant L1210 cells. |
| protein | binds-to | tubulin | A porcine brain protein (35 K protein) which bundles microtubules and its identification as glyceraldehyde 3-phosphate dehydrogenase. |
| link protein | binds-to | hyaluronic | Cartilage proteoglycan aggregate formation. Role of link protein. |
| peptide | binds-to | heparin | Interactions of a laminin-binding peptide from a 33-kDa protein related to the 67-kDa laminin receptor with laminin and melanoma cells are heparin-dependent. |
| protein | binds-to | heat shock | Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines. |
| protein | binds-to | sterol | Localized and inducible expression of Xenopus-posterior (Xpo), a novel gene active in early frog embryos, encoding a protein with a 'CCHC' finger domain. |
| proteins | binds-to | chitin | A conserved domain in arthropod cuticular proteins binds chitin. |
| antiestrogen | binds-to | estrogen | Characterization of the 4-hydroxytamoxifen (4-OHTAM) bound estrogen receptor of MCF-7 cells solubilized by micrococcal nuclease. |
| succinate | binds-to | enzyme | Nuclear magnetic resonance study of ligand binding to Mn-aspartate transcarbamylase. |
| protein | binds-to | ganglioside | Inhibition of protein kinase C-dependent cellular proliferation by interaction of endogenous ganglioside GM1 with the B subunit of cholera toxin. |
| taxol | binds-to | tubulin | Temperature-dependent reversible assembly of taxol-treated microtubules. |
| protein | binds-to | hormone | Age related changes in free plasma testosterone, dihydrotestosterone and oestradiol. |
| enzyme | binds-to | cellulose | Release of the FAD domain from cellobiose oxidase by proteases from cellulolytic cultures of Phanerochaete chrysosporium. |
| protein | binds-to | lipopolysaccharide | Purification and characterization of an endotoxin-binding protein with protease inhibitory activity from Limulus amebocytes. |
| protein | binds-to | thyroglobulin | Insulin and insulin-like growth factor I regulate a thyroid-specific nuclear protein that binds to the thyroglobulin promoter. |
| protein | binds-to | cellulose | Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage. |
| aspartate | binds-to | enzyme | Studies on the mechanism of the glutamine-dependent reaction catalyzed by asparagine synthetase from mouse pancreas. |
| peroxide | binds-to | heme iron | Molecular dynamics simulations of the resting and hydrogen peroxide-bound states of cytochrome c peroxidase. |
| nitrogen | binds-to | 6-position | Nephrotoxicity induced by adenine and its analogs: relationship between structure and renal injury. |
| carbodiimide | binds-to | enzyme | The role of carboxyl groups in the function of endo-beta-1,4-glucanase from Schizophyllum commune. |
| plasminogen | binds-to | streptokinase | Analysis of autoantibodies to plasminogen in the serum of patients with rheumatoid arthritis. |
| protein | binds-to | amiloride | Identification of a processed protein related to the human chaperonins (hsp 60) protein in mammalian kidney. |
| CR | binds-to | proteins | Rapid enzymatic pretreatment of samples before determining chromium in serum or plasma. |
| protein | binds-to | Na | Fluorescence studies of ligand-induced conformational changes of the Na(+)/glucose cotransporter. |
| chromium | binds-to | proteins | Chromium-associated 32P-labeling of proteins. |
| danazol | binds-to | progesterone | Danazol binding to rat androgen, glucocorticoid, progesterone, and estrogen receptors: correlation with biologic activity. |
| anti-androgen | binds-to | rat | The preclinical development of bicalutamide: pharmacodynamics and mechanism of action. |
| anti-androgen | binds-to | androgen | The biological activity of 7 alpha-methyl-19-nortestosterone is not amplified in male reproductive tract as is that of testosterone. |
| 5'-phosphate | binds-to | lysine | Hydrated electron formation on laser excitation of P-pyridoxyl amino acids and proteins. |
| proteins | binds-to | pyrimidine | Multiple sequence-specific single-strand-binding proteins for the promoter region of the rat albumin gene. |
| iodide | binds-to | zinc | X-ray absorption studies of halide binding to carbonic anhydrase. |
| dihydrotestosterone | binds-to | androgen | The androgen receptor: a mediator of diverse responses. |
| protein | binds-to | histone | Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair. |
| protease | binds-to | heparin | Expression and characterization of a serine protease that preferentially cleaves insulin-like growth factor binding protein-5. |
| protein | binds-to | beryllium | Cytochemical study of abnormal intranuclear structures rich in beryllium. |
| enzyme | binds-to | anthranilate | The effects of reversible freezing inactivation and inhibitor binding on redox properties of L-amino-acid oxidase. |
| enzyme | binds-to | polyglutamine | Tissue transglutaminase-catalyzed formation of high-molecular-weight aggregates in vitro is favored with long polyglutamine domains: a possible mechanism contributing to CAG-triplet diseases. |
| protein | binds-to | dihydrotestosterone | The measurement of androgen receptors in human prostatic tissue utilizing sucrose density centrifugation and a protamine precipitation assay. |
| protein | binds-to | matrix proteins | Conserved amphipathic helices near the N-terminus and C-terminus of the alpha subunit of cranin (dystroglycan). |
| desipramine | binds-to | substrate | Solubilization and characterization of the 3H-desipramine binding site of rat phaeochromocytoma cells (PC12-cells). |
| human protein | binds-to | topoisomerase | The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor. |
| human protein | binds-to | retinoblastoma | Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping. |
