Relations corresponding to important

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Relationships for important

Entity 1	Relationship	Entity 2	Document Source
proteins	important	hemostasis	The factor VIII complex: structure and function.
phosphorus	important	pathogenesis	[Experimental vitamin D deficiency with different dietary calcium-phosphorus ratios]
homocysteine	important	pathogenesis	Increased plasma copper in patients with homocystinuria due to cystathionine beta-synthase deficiency.
hypertrophy	important	hyperplasia	Impairment of renal compensatory hypertrophy by hypothyroidism in the rat.
endonuclease	important	tumor	A nuclear localization signal and the C-terminal omega sequence in the Agrobacterium tumefaciens VirD2 endonuclease are important for tumor formation.
atrophy	important	pathogenesis	Structural brain abnormalities in multiple sclerosis patients with major depression.
chickens	important	human campylobacteriosis	Role of real-time molecular typing in the surveillance of Campylobacter enteritis and comparison of pulsed-field gel electrophoresis profiles from chicken and human isolates.
cholesterol	important	reverse cholesterol	Mechanism of cellular phospholipid efflux.
trisaccharide	important	Ca	A sulfated proteoglycan aggregation factor mediates amyloid-beta peptide fibril formation and neurotoxicity.
embryogenesis	important	malformation	Mesp1 expression is the earliest sign of cardiovascular development.
hormone	important	angiotensin	[Aldosterone]
Ras proteins	important	meningioma	Adenovirus-mediated gene transfer of dominant negative Ha-Ras inhibits proliferation of primary meningioma cells.
anhydrase	important	gluconeogenesis	Inhibition of CA V decreases glucose synthesis from pyruvate.
human cancers	important	effective cancer	Etiology-specific gene expression profiles in rat mammary carcinomas.
carcinoma	important	carcinogenesis	Cellular kinetics and gene mutations in gallbladder mucosa with an anomalous junction of pancreaticobiliary duct.
sarcoidosis	important	Japan	Diagnostic routes in cases with single involvement in eyes suspected of sarcoidosis.
mycolic acids	important	pathogenesis	Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis.
syndrome	important	hypopyon	Acute uveitis associated with rifabutin use in patients with human immunodeficiency virus infection.
syndrome	important	skin neoplasms	Hermansky-Pudlak syndrome: report of a case with histological, immunohistochemical and ultrastructural findings.
hypomethylation	important	tumorigenesis	Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.
blood pressure	important	serum cholesterol	Risk factors and raised atherosclerotic lesions in coronary and cerebral arteries. Statistical analysis from the Oslo study.
E. faecium	important	human infections	[Identification of Enterococcus species from clinical samples and their antimicrobial susceptibility]
linoleic acid	important	oleate	Interaction between fish and vegetable oils in relation to rat leucocyte leukotriene production.
oestrogen	important	spermatogenesis	Seminal plasma androgen/oestrogen balance in infertile men.
estrogen	important	stress	Urodynamic and clinical evaluation of postmenopausal women with stress urinary incontinence before and after cyclic estrogen therapy.
proline	important	substrate	Role of the pyrrolidine ring of proline in determining the substrate specificity of cdc2 kinase or cdk5.
enzyme	important	blood pressure	Angiotensin converting enzyme: induction by steroids in rabbit alveolar macrophages in culture.
sterol 27-hydroxylase	important	bile acid	Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene.
lactic acids	important	acidosis	Organic acids in ethylene glycol intoxication.
chronic bacterial infection	important	pathogenesis	Immune complex glomerulonephritis in baboons (Papio cynocephalus) with indwelling intravascular catheters.
Kynurenine aminotransferase	important	tryptophan	Developmental modulation of cysteine conjugate beta-lyase/glutamine transaminase K/kynurenine aminotransferase mRNA in rat brain.
capillary hypertension	important	pathogenesis	Angiotensin converting enzyme inhibitors and progression of chronic renal failure.
6-position	important	substrate	4-Oxalocrotonate tautomerase: pH dependence of catalysis and pKa values of active site residues.
E. coli beta-galactosidase	important	aglycone	Quaternary structure, Mg2+ interactions, and some kinetic properties of the beta-galactosidase from Thermoanaerobacterium thermosulfurigenes EM1.
alpha C protein	important	pathogenesis	Inactivation of the alpha C protein antigen gene, bca, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B Streptococcus.
L-rhamnose	important	substrate	[alpha-L-Rhamnosidase from Fagopyrum esculentum: purification and some properties (author's transl)]
serum triacylglycerol	important	serum cholesterol	Human erythrocyte membrane fluidity and calcium pump activity in primary combined hyperlipidaemia.
L-serine	important	substrate	Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors.
diflunisal	important	rat	Identification of a hydroxy metabolite of diflunisal in rat and human urine.
enzyme	important	exocytosis	Isolation and characterization of a cytosolic phospholipase A2 from bovine adrenal medulla.
enzyme	important	dystrophic epidermolysis bullosa	Recessive dystrophic epidermolysis bullosa: evidence for an altered collagenase in fibroblast cultures.
hypoglycaemia	important	infantile spasms	Decreasing perinatal mortality: unchanged infantile spasm morbidity.
protein	important	hydride	Interdomain hydride transfer in proton-translocating transhydrogenase.
ribose	important	gamma-phosphate	Analysis of the adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase (CobU) enzyme of Salmonella typhimurium LT2. Identification of residue His-46 as the site of guanylylation.
measles	important	pathogenesis	Risk factors in subacute sclerosing panencephalitis: a case-control study.
dysregulation	important	Huntington, NY	Mutant huntingtin increases nuclear corepressor function and enhances ligand-dependent nuclear hormone receptor activation.
malnutrition	important	China	[Follow-up study on children with obesity and hypertension]
Tamm-Horsfall protein	important	pathogenesis	Tamm-Horsfall protein in reflux nephropathy.
middle T antigen	important	oncogenesis	Deletion of proline-rich domain in polyomavirus T antigens results in virus partially defective in transformation and tumorigenesis.
apoptosis	important	leukemogenesis	Expression of the antiapoptosis gene survivin in human leukemia.

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